Modelling the dynamics of population viral load measures under HIV treatment as prevention
نویسندگان
چکیده
منابع مشابه
Using HIV viral load to guide treatment-for-prevention interventions.
PURPOSE OF REVIEW To provide evidence that HIV-1 RNA load can guide treatment-for-prevention interventions to mitigate the HIV epidemic. RECENT FINDINGS Some HIV-infected individuals maintain increased levels of HIV-1 RNA load after acute infection for an extended period of time, and can disproportionately contribute to the spread of HIV in the community. The recent HIV Prevention Trials Netw...
متن کاملTen Year Trends in Community HIV Viral Load in Barbados: Implications for Treatment as Prevention
BACKGROUND Treatment as prevention is a paradigm in HIV medicine which describes the public health benefit of antiretroviral therapy (ART). It is based on research showing substantial reductions in the risk of HIV transmission in persons with optimally suppressed HIV-1 Viral Loads (VL). The present study describes ten year VL trends at the national HIV treatment unit and estimates VL suppressio...
متن کاملHIV elimination and population viral load.
www.thelancet.com/hiv Vol 3 November 2016 e507 WHO and UNAIDS have recommended treatment as pre vention for the global elimination of HIV. Treatment suppresses an individuals’ viral load, making them less infectious. The higher the coverage of treatment, the lower the viral load in the population, and the lower the incidence of new infections. Incidence is very diffi cult to measure directly as...
متن کاملUse of the community viral load as a population-based biomarker of HIV burden.
OBJECTIVES Recent data suggest that community viral load (CVL) can be used as a population-level biomarker for HIV transmission and its reduction may be associated with a decrease in HIV incidence. Given the magnitude of the HIV epidemic in Washington, District of Columbia, we sought to measure the District of Columbia's CVL. DESIGN An ecological analysis was conducted. METHODS Mean and tot...
متن کاملTreatment as prevention in resource-limited settings: is it feasible to maintain HIV viral load suppression over time?
INTRODUCTION Recently, there has been increasing interest in the role of "treatment as prevention" (TasP). Some of the questions regarding TasP strategies arise from the perceived difficulties in achieving and maintaining viral load (VL) suppression over time and the risk of emergence of viral resistance that could compromise future treatment options. This study was conducted to assess these qu...
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ژورنال
عنوان ژورنال: Infectious Disease Modelling
سال: 2018
ISSN: 2468-0427
DOI: 10.1016/j.idm.2018.09.001